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(#co-first author; *corresponding author; undergraduate co-authors)

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At The University of Arizona since April 2019

2024

38. Z Wang, W Li, Y Jiang, J Park, K.M. Gonzalez, X. Wu, Q-Y Zhang, J. Lu. Cholesterol-modified sphingomyelin chimeric lipid bilayer for improved therapeutic delivery.

Nature Communications, 2024. 10.1038/s41467-024-46331-7. 

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37. Z Wang, W Li, Y Jiang, TB Tran, J Chung, M Kim, AJ Scott, J Lu. Camptothesome-based combination nanotherapeutic regimen for improved colorectal cancer immunochemotherapy.

Biomaterials, 2024. 122477. 

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2023

36. Y Jiang, W Li, Z Wang, J Lu. ​Lipid-Based Nanotechnology: Liposome. Pharmaceutics. 2023; 16 (1), 34

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35. Wang, Z., Li, W., Jiang, Y., Tran, Y.B., Cordova, L.E., Chung, J., Kim, M., Wondrak, G., Erdrich, J., Lu, J*. Sphingomyelin-derived nanovesicles for the delivery of the IDO1 inhibitor epacadostat enhance metastatic and post-surgical melanoma immunotherapy. Nature Communications. 2023; 14 (1), 7235.

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34. Wang, Z., Gonzalez, K.M., Cordova, L.E., Lu, J*. Nanotechnology-empowered therapeutics targeting neurodegenerative diseases and aging. WIREs Nanomedicine and Nanobiotechnology (Wiley). 2023 Sep-Oct;15(5):e1907. doi: 10.1002/wnan.1907. 

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33. Jiang, T., Gonzalez, K.M., Cordova, L.E., Lu, J*. Nanotechnology-enabled gene delivery for cancer and other genetic diseases. Expert Opinion on Drug Delivery. . DOI:10.1080/17425247.2023.2200246

 

32. Li, W., Jiang, Y., Lu, J*.Nanotechnology-enabled immunogenic cell death for improved cancer immunotherapy. International Journal of Pharmaceutics. 2023 Jan 28:122655. doi: 10.1016/j.ijpharm.2023.122655. 

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2022

31. Wang, Z., Cordova, L.E., Chalasani, P., Lu, J*. Camptothesome Potentiates PD-L1 Immune Checkpoint Blockade for Improved Metastatic Triple Negative Breast Cancer Immunochemotherapy. Molecular Pharmaceutics. 2022;19(12):4665-4674. PMID: 36413426

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30. Li, W., Gonzalez, K.M., Chung, J., Kim, M., Lu, J*. Surface-Modified Nanotherapeutics Targeting Atherosclerosis. Biomaterials Science (Emerging Investigator Series). 2022, 10, 5459 2022. DOI: 10.1039/D2BM00660J

 

29. Wang, Z., Park, J., Gonzalez, K.M., Scott, A.J., Lu, J*. Camptothesome Elicits Immunogenic Cell Death and Potentiates Immune Checkpoint Blockade for Enhanced Metastatic Colorectal Cancer Therapy. Journal of Controlled Release. 2022, S0168-3659 (22) 00478-3. PMID: 35926754. Article access link: https://authors.elsevier.com/a/1fYdrcI2%7E%7EIyl

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2021

28. Wang, Z., Little, N., Chen, J., Lambesis, K.T., Le, K.T., Han, W.,  Scott, A.J., Lu, J*.  Immunogenic camptothesome nanovesicles comprising sphingomyelin-derived camptothecin bilayers for safe and synergistic cancer immunochemotherapy. Nature Nanotechnology, August 12, 2021. PMID: 34385682. Article access link: https://rdcu.be/ctWld; https://doi.org/10.1038/s41565-021-00950-z 

 

27. Li, W., Little, N., Park, J., Foster, C.A., Chen, J., Lu, J.*.,Tumor-Associated Fibroblast-Targeting Nanoparticles for Enhancing Solid Tumor Therapy: Progress and Challenges. Molecular Pharmaceutics, 2021, 18, 8, 2889–2905. PMID: 34260250

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2020

26. Wang, Z., Chen, J., Little, N., Lu, J*., "Self-assembling Prodrug Nanotherapeutics for Synergistic Tumor Targeted Drug Delivery.", Acta Biomaterialia, 2020, 111, 20-28. PMID: 32454086

PMCID: PMC7245299

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Prior to The University of Arizona

 2019

25. Liu, Q., X. Wang, X. Liu, S. Kumar, G. Gochman, Y. Ji, Y-P. Liao, C. Hyun Chang, W. Situ, Lu, J, et al., "Use of Polymeric Nanoparticle Platform Targeting the Liver To Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model.", ACS Nano, vol. 13, issue 4, pp. 4778-94, 2019 04 23.  PMID: 30964276 PMCID: PMC6506187

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24. Ji, Y., X. Liu, M. Huang, J. Jiang, Y-P. Liao, Q. Liu, C. Hyun Chang, H. Liao, Lu, J, X. Wang, et al., "Development of self-assembled multi-arm polyrotaxanes nanocarriers for systemic plasmid delivery in vivo.", Biomaterials, vol. 192, pp. 416-28, 2019 02.  PMID: 30500723 PMCID: PMC6934403

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23. Liu, X., J. Jiang, R. Chan, Y. Ji, Lu, J, Y-P. Liao, M. Okene, J. Lin, P. Lin, C. Hyun Chang, et al., "Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer.", ACS Nano, vol. 13, issue 1, pp. 38-53, 2019 01 22. PMID: 30525443 PMCID: PMC6554030

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22. Wang, X., C. Hyun Chang, J. Jiang, Q. Liu, Y-P. Liao, Lu, J, L. Li, X. Liu, J. Kim, A. Ahmed, et al., "The Crystallinity and Aspect Ratio of Cellulose Nanomaterials Determine Their Pro-Inflammatory and Immune Adjuvant Effects In Vitro and In Vivo.", Small, vol. 15, issue 42, pp. e1901642, 2019 10.  PMID: 31461215 PMCID: PMC6800804

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2018

21. Wang, X., J-H. Lee, R. Li, Y-P. Liao, J. Kang, C. Hyun Chang, L. M. Guiney, V. Mirshafiee, L. Li, Lu, J, et al., "Toxicological Profiling of Highly Purified Single-Walled Carbon Nanotubes with Different Lengths in the Rodent Lung and Escherichia Coli.", Small, vol. 14, issue 23, pp. e1703915, 2018 06.  PMID: 29733549 PMCID: PMC6239219

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2017

20. Jiang, W., X. Wang, O. J. Osborne, Y. Du, C. Hyun Chang, Y-P. Liao, B. Sun, J. Jiang, Z. Ji, R. Li, X. Liu, Lu, J, et al., "Pro-Inflammatory and Pro-Fibrogenic Effects of Ionic and Particulate Arsenide and Indium-Containing Semiconductor Materials in the Murine Lung.", ACS Nano, vol. 11, issue 2, pp. 1869-83, 2017 02 28.  PMID: 28177603 PMCID: PMC5543990

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19. Lu, J, X. Liu, Y-P. Liao, F. Salazar, B. Sun, W. Jiang, C. Hyun Chang, J. Jiang, X. Wang, A. M. Wu, et al., "Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression.", Nature Communications, vol. 8, issue 1, pp. 1811, 2017 11 27. 

PMID: 29180759 PMCID: PMC57038457

 

18. Liu, J Jiang, Y Ji, Lu, J, R Chan, H Meng., "Targeted drug delivery using iRGD peptide for solid cancer treatment.", Molecular systems design & engineering, vol. 2, issue 4, pp.370-79. 2017 10 1. PMCID: 30498580 PMID: PMC6258069

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2016

17. Gao, X., P. Zhang, X. Zhang, Y. Huang, Lu, J, and S. Li, "Functional surfactants: designing principles and applications in constructing nanomedicines", Nanomedicine: Nanotechnology, Biology and Medicine, vol. 12, issue 2, 2016 2. DOI: 10.1016/j.nano.2015.12.033

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2015

16. Lu, J, C Liu, P Wang, M Ghazwani, J Xu, Y Huang, X Ma, P Zhang, S Li., "The self-assembling camptothecin-tocopherol prodrug: an effective approach for formulating camptothecin", Biomaterials vol. 62, pp. 176-87, 2015 9. PMID: 26057133 PMCID: PMC4470812

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15. He, C., Lu, J, and W. Lin, "Hybrid nanoparticles for combination therapy of cancer", Journal of Controlled Release, vol. 219, pp. 224-36, 2015 10 10.  PMID: 26387745 PMCID: PMC4656047

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2014

14. Lu, J, W. Zhao, Y. Huang, H. Liu, R. Marquez, R. B. Gibbs, J. Li, R. Venkataramanan, L. Xu, S. Li, et al., "Targeted delivery of Doxorubicin by folic acid-decorated dual functional nanocarrier.", Molecular Pharmaceutics, vol. 11, issue 11, pp. 4164-78, 2014 Nov 03.  PMID: 25265550 PMCID: PMC4224520

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13. Lu, J, W. Zhao, H. Liu, R. Marquez, Y. Huang, Y. Zhang, J. Li, W. Xie, R. Venkataramanan, L. Xu, et al., "An improved D-α-tocopherol-based nanocarrier for targeted delivery of doxorubicin with reversal of multidrug resistance.", Journal of Controlled Release, vol. 196, pp. 272-86, 2014 Dec 28.  PMID: 25456831 PMCID: PMC4267990

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12. Zhang, P., Y. Huang, H. Liu, R. T. Marquez, Lu, J, W. Zhao, X. Zhang, X. Gao, J. Li, R. Venkataramanan, et al., "A PEG-Fmoc conjugate as a nanocarrier for paclitaxel", Biomaterials, vol. 35, issue 25, pp. 7146-56, 2014 8. PMID: 24856103 PMCID: PMC4102141

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11. Zhang, X., Y. Huang, W. Zhao, H. Liu, R. Marquez, Lu, J, P. Zhang, Y. Zhang, J. Li, X. Gao, et al., "Targeted delivery of anticancer agents via a dual function nanocarrier with an interfacial drug-interactive motif.", Biomacromolecules, vol. 15, issue 11, pp. 4326-35, 2014 11 10.  PMID: 25325795 PMCID: PMC4229023

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10. Y Zhang, Y Huang, W Zhao, Lu, J, P Zhang, X Zhang, J Li, X Gao, et al.,"Fmoc-Conjugated PEG-Vitamin E2 Micelles for Tumor-Targeted Delivery of Paclitaxel: Enhanced Drug-Carrier Interaction and Loading Capacity", The AAPS journal, vol. 16, issue 6, pp. 1282-91, 2014 11. PMID: 25193267 PMCID: PMC4389742

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9. Y Chen, X Zhang, Lu, J, Y Huang, J Li, S Li, "Targeted delivery of curcumin to tumors via PEG-derivatized FTS-based micellar system", The AAPS journal, vol. 16, issue 3, pp. 600-08, 2014 5. PMID: 24706375 PMCID: PMC4012035

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8. P Zhang, Lu, J, Y Huang, W Zhao, Y Zhang, X Zhang, J Li, et al., "Design and Evaluation of a PEGylated Lipopeptide Equipped with Drug-Interactive Motifs as an Improved Drug Carrier", 

The AAPS Journal, vol. 16, issue 1, pp.114-24, 2014 1. PMID: 24281690 PMCID: PMC3889538

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2013

7. Lu, J#, Y. Huang#, W. Zhao, R. T. Marquez, X. Meng, J. Li, X. Gao, R. Venkataramanan, Z. Wang, and S. Li, "PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers.", Biomaterials, vol. 34, issue 5, pp. 1591-600, 2013 2.  PMID: 23182923 PMCID: PMC3529003. 

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6. Lu, J#, Y. Huang#, W. Zhao, Y. Chen, J. Li, X. Gao, R. Venkataramanan, and S. Li, "Design and characterization of PEG-derivatized vitamin E as a nanomicellar formulation for delivery of paclitaxel.", Molecular Pharmaceutics, vol. 10, issue 8, pp. 2880-90, 2013 8 05.  PMID: 23768151 PMCID: PMC3778165. 

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5. X Zhang, Lu, J, Y Huang, W Zhao, Y Chen, J Li, X Gao, et al., "PEG-farnesylthiosalicylate conjugate as a nanomicellar carrier for delivery of paclitaxel", Bioconjugate Chemistry, vol 24, issue 3, pp. 464-72, 2013 3. PMID: 23425093 PMCID: PMC3623935

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4. J Li, Lu, J, Y Zhang, M Ghazwani, P Zhang, X Gao, S Li, "RNAi in Liver Diseases", Advanced Delivery and Therapeutic Applications of RNAi, pp.327-366.

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3. J Li, M Ghazwani, Y Zhang, Lu, J, J Li, J Fan, CR Gandhi, S Li, "miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression", Journal of Hepatology, vol 58, issue 3, pp. 522-528, 2013 3.  PMID: 23178710 PMCID: PMC3619187

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2. X Gao, Y Huang, AM Makhov, M Epperly, Lu, J, S Grab, P Zhang, L Rohan, et al.,"Nanoassembly of Surfactants with Interfacial Drug-Interactive Motifs as Tailor-Designed Drug Carriers", Molecular Pharmaceutics, vol 10, issue 1, pp. 187-98, 2013 1.  PMID: 23244299 PMCID: PMC3540186

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2012

1. Y Huang#, Lu, J#, X Gao, J Li, W Zhao, M Sun, DB Stolz, R Venkataramanan, et al., "PEG-Derivatized Embelin as a Dual Functional Carrier for the Delivery of Paclitaxel", Bioconjugate Chemistry, vol 23, issue 7, pp. 1443-1451. 2012 7.  PMID: 22681537 PMCID: PMC3399921.

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